Edition revue de : Tietz textbook of clinical chemistry.

R�ef. bibliogr. Index.

Sect. I. Laboratory principles. Introduction to principles of laboratory analyses and safety -- Specimen collection and processing -- sect. II. Analytical techniques and instrumentation. Optical techniques -- Electrochemistry and chemical sensors -- Electrophoresis -- Chromatography -- Mass spectrometry -- Principles of clinical enzymology -- Principles of immunochemical techniques -- Nanotechnology and microfabrication -- Automation in the clinical laboratory -- Point-of-care testing -- sect. III. Principles of laboratory medicine. Introduction to laboratory medicine and evidence-based laboratory medicine -- Selection and analytical evaluation of methods with statistical techniques -- Clinical evaluation of methods -- Establishment and use of reference values -- Preanalytical variables and biological variation -- Clinical laboratory informatics -- Quality management -- sect. IV. Analytes. Amino acids, peptides, and proteins -- Enzymes -- Cytokines -- Tumor markers -- Kidney function tests -- Carbohydrates -- Lipids, lipoproteins, apolipoprotens, and other cardiovascular risk factors -- Electrolytes and blood gases -- Hormones -- Catecholamines and serotonin -- Vitamins and trace elements -- Hemoglobin, iron, and bilirubin -- Porphyrins and disorders of porphyrin metabolism -- Therapeutic drugs and their management -- Clinical toxicology -- Toxic metals -- sect. V. Molecular diagnostics and genetics. Principles of molecular biology and approaches to nucleic acid isolation -- Nucleic acid techniques -- Design and operation of the molecular diagnostics laboratory -- Molecular genetics and diagnosis of hematopoietic neoplasms -- Inherited diseases -- Identity assessment -- Molecular methods in diagnosis and monitoring of infectious diseases -- Pharmacogenetics -- sect. VI. Pathophysiology. Cardiac function -- Kidney disease -- Physiology and disorders of water, electrolyte, and acid-base metabolism -- Liver disease -- Gastric, pancreatic, and intestinal function -- Mineral and bone metabolism -- Pituitary function -- The adrenal cortex -- The thyroid: pathophysiology and thyroid function testing -- Reproductive related disorders -- Clinical chemistry of pregnancy -- Inborn errors of amino acid, organic acid, and fatty acid metabolism -- sect. VII. Appendix. Reference information for the clinical laboratory